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ADVANTAGE

Active Ingredient	Imidacloprid
Category	Ectoparasiticides
Target Specificity	Dog, Cat
Web Address	http://www.nofleas.com
Mode of Action	Imidacloprid has a high affinity for the nicotinergic acetylcholine receptors in the post-synaptic region of the central nervous system (CNS). The ensuing inhibition of cholinergic transmission in insects results in paralysis and death.
Indication/Description	For the prevention and treatment of flea infestations on dogs&cats. Fleas on are killed within one day following treatment. One treatment prevents further flea infestation for four weeks. The product can be used as part of a treatment strategy for flea allergy dermatitis.
CAS No	138261-41-3
Chemical Name	-(6-Chloro-3-pyridylmethyl)-N-nitro-imidazolidin-2-ylideneamine
Chemical Structure
Method of Administration	Part the hair on the animal's neck at the base of the skull until the skin is visible. Place the tip of the tube on the skin and squeeze firmly several times to empty the contents directly onto the skin. Apply only to undamaged skin. Do not allow recently treated animals to groom each other.
Dosage	10 mg/ kg body weight topical solution (0.4 ml of the 10 % solution to cats under 9lbs body weight, 0.8 ml of the 10 % solution to cats over 9lbs of body weight, 0.4 ml of the 10 % solution to dogs 10lbs and under, 1,0 ml of the 10 % solution to dogs between 11 - 20lbs of body weight, 2,5ml of the 10 % solution to dogs 21-55lbs of body weight, 4,0ml of the 10 % solution to dogs over 55lbs of body weight).