Font size
click to adjust
Page tools
Search
Product Search
Information on veterinary pharmaceutical products:For more search options
Our Products
PROFENDER Cat
| Active Ingredient | ||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Category | ||||||||||||||||||||||||||
| Target Specificity | ||||||||||||||||||||||||||
| Web Address | www.profender.no | |||||||||||||||||||||||||
| Mode of Action | Emodepside is a semi-synthetic compound belonging to the new chemical group of depsipeptides. It is active against roundworms (ascarids and hookworms). In this product, emodepside is responsible for the efficacy against Toxocara cati, Toxascaris leonina, and Ancylostoma tubaeforme. It acts at the neuromuscular junction by stimulating presynaptic receptors belonging to the secretin receptor family which results in paralysis and death of the parasites. Praziquantel is a pyrazinoisoquinoline derivative effective against tapeworms such as Dipylidium caninum, Echinococcus multilocularis, and Taenia taeniaeformis. Praziquantel is rapidly adsorbed via the surface of the parasites and acts primarily by changing the Ca++ permeability of the parasite membranes. This results in severe damage to the parasite integument, contraction and paralysis, disruption of metabolism and finally leads to the death of the parasite. | |||||||||||||||||||||||||
| Indication/Description | For cats suffering from, or at risk from, mixed parasitic infections caused by roundworms and tapeworms of the following species: Roundworms (Nematodes) Toxocara cati (mature adult, immature adult, L4 and L3) Toxascaris leonina (mature adult, immature adult and L4) Ancylostoma tubaeforme (mature adult, immature adult and L4) Tapeworms (Cestodes) Dipylidium caninum (adult) Taenia taeniaeformis (adult) Echinococcus multilocularis (adult) | |||||||||||||||||||||||||
| CAS No | therapeutic antiparasitic agent; ATCvet code: QP52AA51 | |||||||||||||||||||||||||
| Chemical Name | Praziquantel: 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin- 4-one Emodepside: C60H90N6O14 | |||||||||||||||||||||||||
| Chemical Structure | Praziqunatel & Emodepside:   | |||||||||||||||||||||||||
| Formulations | Profender contains 21.4 mg/ml emodepside and 85.8 mg/ml praziquantel. | |||||||||||||||||||||||||
| Presentation | Each unit dose (pipette) of Profender delivers:
| |||||||||||||||||||||||||
| Method of Administration | For external use only. Remove one pipette from package. Hold pipette in upright position, twist and pull off cap and use the opposite end of the cap to break the seal. Part the fur on the cat’s neck at the base of the skull until the skin is visible. Place the tip of the pipette on the skin and squeeze firmly several times to empty the contents directly onto the skin. Application on the base of the skull will minimise the ability of the cat to lick the product off. | |||||||||||||||||||||||||
| Dosage | The recommended minimum doses are 3 mg emodepside / kg body weight and 12 mg praziquantel / kg body weight, equivalent to 0.14 ml Profender / kg body weight.
| |||||||||||||||||||||||||